| Identification | More | [Name]
4,4-Diethoxy-N,N-dimethyl-1-butanamine | [CAS]
1116-77-4 | [Synonyms]
1-BUTANAMINE 4,4-DIETHOXY-N,N-DIMETHYL
(4,4-DIETHOXY-BUTYL)-DIMETHYL-AMINE
4,4-DIETHOXY-N,N-DIMETHYL-1-BUTANAMINE
4,4-DIETHOXY-N,N-DIMETHYLBUTANAMINE
4,4-DIETHOXY-N, N-DIMETHYL-BUTYLAMINE
4-DIMETHYLAMINO BUTANAL DIETHYL ACETAL
4-DIMETHYLAMINO BUTYRALDEHYDE DIETHYL ACETAL
4-(N,N-DIMETHYLAMINO)BUTANAL DIETHYL ACETAL
N, N-DIMETHYL-4,4-DIETHOXY-1-BUTANAMINE
N,N-DIMETHYL-4-AMINOBUTANAL DIETHYL ACETAL
1-Butanamine, 4,4-diethoxy-N,N-dimethyl-S
4,4-Diethoxy-N,N-dimethyl-1-butanamine(DDBA)
4-DimethylamineButyaldehydeDimethylAcetal(ForSumatriptan)
1-Butanamine,4,4-diethoxy-N,N-
4,4-diethoxy-N,N-dimethyl-butylamine (intermediate of zolmitriptan and sumatriptan)
4-(N,N-DIMETHYLAMINO)BUTANAL DIETHYL ACETAL(FOR ZOLMITRIPTAN AND OTHER TRIPTANS)
4-(N,N-DIMETHYLAMINO)-BUTYRALDEHYDE DIETHYL ACETAL
4-N,N-DIMETHYLAMINOBUTANAL DIETHYL ACETAL (FOR SUMATRIPTAN, RIZATRIPTAN, ZOLMITRIPTAN)
4-N,N-dimethylaminobutanal diethyl acetal ( For Triptans )
4,4-DIETHOXY-N,N-DIMETHYL BUTYLAMINE,GC 96+% | [EINECS(EC#)]
601-109-1 | [Molecular Formula]
C10H23NO2 | [MDL Number]
MFCD00671479 | [Molecular Weight]
189.3 | [MOL File]
1116-77-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,C | [Risk Statements ]
R41:Risk of serious damage to eyes.
R34:Causes burns.
R10:Flammable. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 3267 8 / PGIII | [WGK Germany ]
3
| [HS Code ]
29225090 |
| Hazard Information | Back Directory | [Chemical Properties]
Light yellow liquid | [Uses]
4,4-Diethoxy-N,N-dimethyl-1-butanamine is used in the preparation of N,N-Dimethyltryptamines, 5-HT1D receptor agonists, for medicinal treatments such as antimigraine drugs(Sumatriptan, Rizatriptan, Almotriptan, Zolmitriptan).
| [Uses]
4-Dimethylaminobutyraldehyde Diethyl Acetal (Zolmitriptan USP Related Compound H) is used in the preparation of N,N-Dimethyltryptamines, 5-HT1D receptor agonists, for medicinal treatments such as antimigraine drugs. | [Uses]
intermediate for Sumatriptan, Rizatriptan, Almotriptan, Zolmitriptan | [Application]
4-Dimethylaminobutyraldehyde Diethyl Acetal (Zolmitriptan USP Related Compound H) is used in the preparation of N,N-Dimethyltryptamines, 5-HT1D receptor agonists, for medicinal treatments such as antimigraine drugs. | [Preparation]
4-Dimethylaminobutyraldehyde diethyl acetal synthesis: The reaction of 1-bromo-3-chloro propane and dimethylamine solution with PEG as a phase transfer catalyst, and obtained 3-dimethylamino-1-chloro propane. 3-dimethylamino-1-chloro propane reacted with magnesium and Grinard reagent was acquired. 4-Dimethylaminobutyraldehyde diethyl acetal is obtained by the reaction of Grinard reagent and triethyl orthoformate. The yield was 70.11%. | [Synthesis Reference(s)]
Tetrahedron Letters, 35, p. 2401, 1994 DOI: 10.1016/0040-4039(94)85230-8 |
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