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ChemicalBook--->CAS DataBase List--->109028-10-6

109028-10-6

109028-10-6 Structure

109028-10-6 Structure
IdentificationBack Directory
[Name]

CGS 12066B DIMALEATE
[CAS]

109028-10-6
[Synonyms]

CGS 12066B
Cgs 12066a
CGS-12066A MALEATE
CGS 12066B DIMALEATE
CGS-12066A MALEATE 5HT1B SEROTONIN RECEP
7-TRIFLUOROMETHYL-4-(4-METHYL-1-PIPERAZINYL)PYRROLOL(1,2-A)QUINOXALINE
7-TRIFLUOROMETHYL-4-(4-METHYL-1-PIPERAZINYL)PYRROLO-(1,2-A)QUINOXALINE MALEATTE
7-TRIFLUOROMETHYL-4-(4-METHYL-1-PIPERAZINYL)PYRROLO[1,2-A]-QUINOXALINE DIMALEATE
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate
Pyrrolo(1,2-A)quinoxaline, 4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-, (Z)-2-butenedioate (1:2)
[Molecular Formula]

C25H25F3N4O8
[MDL Number]

MFCD00055048
[MOL File]

109028-10-6.mol
[Molecular Weight]

566.48
Chemical PropertiesBack Directory
[Melting point ]

126-127℃
[density ]

1.3424 (estimate)
[storage temp. ]

Store at RT
[solubility ]

H2O: 1.4 mg/mL
[form ]

solid
[color ]

white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

CGS 12066B dimaleate is a selective SR-1B agonist.
[Biological Activity]

5-HT 1B full agonist, 10-fold selective over 5-HT 1A and 1000-fold selective over 5-HT 2C receptors. Centrally active following systemic administration.
[IC 50]

5-HT1B Receptor: 51 nM (IC50)
[storage]

Store at RT
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