| Identification | Back Directory | [Name]
CINANSERIN HYDROCHLORIDE | [CAS]
1166-34-3 | [Synonyms]
DPTC
CINANSERIN
Cinanserine
DPTC HYDROCHLORIDE
CINANSERIN HYDROCHLORIDE
2'-(3-DIMETHYLAMINOPROPYL-THIO)-CINNAMANILIDE HYDROCHLORIDE
N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]-3-phenylpropenamide
N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE
2-Propenamide, N-[2-[[3-(dimethylamino)propyl]thio]phenyl]-3-phenyl-
N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE HYDROCHLORIDE | [Molecular Formula]
C20H24N2OS | [MDL Number]
MFCD00055609 | [MOL File]
1166-34-3.mol | [Molecular Weight]
340.48 |
| Chemical Properties | Back Directory | [Melting point ]
82-83 °C | [Boiling point ]
519.5±50.0 °C(Predicted) | [density ]
1.13±0.1 g/cm3(Predicted) | [RTECS ]
UC6323000 | [storage temp. ]
Desiccate at RT | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.46±0.70(Predicted) | [color ]
White to Off-White | [Water Solubility ]
Soluble to 50 mM in water |
| Hazard Information | Back Directory | [Uses]
A 5-HT antagonist | [Uses]
Serotonin
inhibitor. | [Definition]
ChEBI: Cinanserin is an aryl sulfide that is (2E)-3-phenyl-N-(2-sulfanylphenyl)prop-2-enamide in which the hydrogen of the thiol group is substituted by a 3-(dimethylamino)propyl group. It is a 5-hydroxytryptamine receptor antagonist and an inhibitor of SARS-CoV replication. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an antiviral agent and an anticoronaviral agent. It is a tertiary amino compound, a secondary carboxamide, a member of cinnamamides and an aryl sulfide. It is a conjugate base of a cinanserin(1+). | [Biological Activity]
5-HT 2 antagonist. |
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