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ChemicalBook--->CAS DataBase List--->1166-34-3

1166-34-3

1166-34-3 Structure

1166-34-3 Structure
IdentificationBack Directory
[Name]

CINANSERIN HYDROCHLORIDE
[CAS]

1166-34-3
[Synonyms]

DPTC
CINANSERIN
Cinanserine
DPTC HYDROCHLORIDE
CINANSERIN HYDROCHLORIDE
2'-(3-DIMETHYLAMINOPROPYL-THIO)-CINNAMANILIDE HYDROCHLORIDE
N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]-3-phenylpropenamide
N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE
2-Propenamide, N-[2-[[3-(dimethylamino)propyl]thio]phenyl]-3-phenyl-
N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE HYDROCHLORIDE
[Molecular Formula]

C20H24N2OS
[MDL Number]

MFCD00055609
[MOL File]

1166-34-3.mol
[Molecular Weight]

340.48
Chemical PropertiesBack Directory
[Melting point ]

82-83 °C
[Boiling point ]

519.5±50.0 °C(Predicted)
[density ]

1.13±0.1 g/cm3(Predicted)
[RTECS ]

UC6323000
[storage temp. ]

Desiccate at RT
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

13.46±0.70(Predicted)
[color ]

White to Off-White
[Water Solubility ]

Soluble to 50 mM in water
Hazard InformationBack Directory
[Uses]

A 5-HT antagonist
[Uses]

Serotonin inhibitor.
[Definition]

ChEBI: Cinanserin is an aryl sulfide that is (2E)-3-phenyl-N-(2-sulfanylphenyl)prop-2-enamide in which the hydrogen of the thiol group is substituted by a 3-(dimethylamino)propyl group. It is a 5-hydroxytryptamine receptor antagonist and an inhibitor of SARS-CoV replication. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an antiviral agent and an anticoronaviral agent. It is a tertiary amino compound, a secondary carboxamide, a member of cinnamamides and an aryl sulfide. It is a conjugate base of a cinanserin(1+).
[Biological Activity]

5-HT 2 antagonist.
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