| Identification | Back Directory | [Name]
GOITRINE | [CAS]
1072-93-1 | [Synonyms]
GOITRINE
R-GOITRIN
D-Goitrin
Epigotrin
Epigoitrin
BA-51-090278
R、Sepigoitrin
Goitrine
Epigoitrin
Epigoitrin/(R,S)-goitrin
5-VINYL-2-THIOOXAZOLIDONE
(-)5-VINYL-2-OXAZOLIDINETHIONE
(R)-5-Vinyl-2-oxazolidinethione
(5R)-5-Vinyloxazolidine-2-thione
(5R)-5β-Vinyloxazolidine-2-thione
(R)-5-Ethenyl-2-oxazolidinethione
2-Oxazolidinethione, 5-ethenyl-, (5R)-
Goitrine, 98%, from Isatis indigotica Fortune | [Molecular Formula]
C5H7NOS | [MDL Number]
MFCD01709801 | [MOL File]
1072-93-1.mol | [Molecular Weight]
129.18 |
| Chemical Properties | Back Directory | [Melting point ]
47.5°C | [Boiling point ]
150.6±43.0 °C(Predicted) | [density ]
1.170 (estimate) | [refractive index ]
1.5480 (estimate) | [storage temp. ]
Amber Vial, -20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
solid | [pka]
13.34±0.40(Predicted) | [color ]
White to Off-White |
| Safety Data | Back Directory | [Safety Statements ]
24/25 | [HS Code ]
29349990 | [Toxicity]
mouse,LD50,unreported,1260mg/kg (1260mg/kg),Journal of Agricultural and Food Chemistry. Vol. 17, Pg. 483, 1969. |
| Hazard Information | Back Directory | [Uses]
Goitrine is a cyclic thiocarbamate that is seen reducing production of thyroid hormones. | [Definition]
ChEBI:(R)-goitrin is a 5-ethenyl-1,3-oxazolidine-2-thione that has R-configuration. It is a constituent of a traditional Chinese herbal medicine, Radix isatidis. It has a role as an antiviral agent and a plant metabolite. It is an enantiomer of a (S)-goitrin. | [Biological Activity]
Epigoitrin is a sulfur containing alkaloid isolated from Isatis indigotica (Ban Lan Gen) th at exhibits antiviralanticancerand antithyroid activities. Epigoitrin significantly decreases the susceptibility of restraint mice to H1N1 influenza virus. Epigoitrin and goitrin appear to show virucidal effect on influenza virus A (H1N1) in vitro and in ovo. | [target]
Influenza virus | [storage]
4°C, protect from light |
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