| Identification | More | [Name]
O-PHOSPHORYLETHANOLAMINE | [CAS]
1071-23-4 | [Synonyms]
2-AMINOETHANOL DIHYDROGEN PHOSPHATE
2-AMINOETHYL DIHYDROGEN PHOSPHATE
2-HYDROXYETHYLAMINE ACID PHOSPHATE
2-HYDROXYETHYLAMMONIUM DIHYDROGEN PHOSPHATE
COLAMINE ACID PHOSPHATE
COLAMINE PHOSPHORIC ACID
ETHANOLAMINE ACID PHOSPHATE
ETHANOLAMINE DIHYDROGEN PHOSPHATE
ETHANOLAMINE PHOSPHATE
MONOETHANOLAMINE ACID PHOSPHATE
O-PHOSPHOCOLAMINE
O-PHOSPHOETHANOLAMINE
O-PHOSPHORYLETHANOLAMINE
PHOSPHOCOLAMINE
PHOSPHOETHANOLAMINE
PHOSPHORYL COLAMINE
PHOSPHORYLETHANOLAMINE
2-amino-ethanodihydrogenphosphate(ester)
2-amino-ethanophosphate
Colamine phosphate | [EINECS(EC#)]
213-988-5 | [Molecular Formula]
C2H8NO4P | [MDL Number]
MFCD00008178 | [Molecular Weight]
141.06 | [MOL File]
1071-23-4.mol |
| Safety Data | Back Directory | [Hazard Codes ]
T,C | [Risk Statements ]
R25:Toxic if swallowed.
R34:Causes burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S27:Take off immediately all contaminated clothing . | [RIDADR ]
UN 3261 8/PG 2
| [WGK Germany ]
3
| [RTECS ]
KJ5830000
| [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29221990 | [Toxicity]
LD50 orally in Rabbit: 5820 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
O-PHOSPHORYLETHANOLAMINE is white powder
| [Uses]
O-PHOSPHORYLETHANOLAMINEe is used in the synthesis of Sphingomyelin, a type of sphingolipid found in animal cell membrane.
| [Definition]
ChEBI: The ethanolamine mono-ester of phosphoric acid, and a metabolite of phospholipid metabolism. This phosphomonoester shows strong structural similarity to the inhibitory neurotransmitter GABA, and is decreased in post-mortem Alzheimer's disease brain. | [General Description]
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com. | [Biochem/physiol Actions]
Phosphorylethanolamine participates in phospholipid metabolism. Its release can be stimulated occasionally by depolarizing stimuli. Reduction of phosphorylethanolamine levels has been observed in Alzheimer′s and Huntington′s disease. | [storage]
Store at -20°C,protect from light | [Purification Methods]
Purification by recrystallisation from aqueous EtOH gives a hydrate (m 140-141o). Its solubility in H2O is 17% and 0.003% in MeOH or EtOH at 22o. [F.lisch & .sterberg J Biol Chem 234 2298 1959, Baer & Staucer Can J Chem 34 434 1956, Christensen J Biol Chem 135 399 1940.] It is a potent inhibitor of ornithine decarboxylase [Gilad & Gilad Biochem Biophys Res Commun 122 277 1984]. [Beilstein 4 IV 1415.] |
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