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ChemicalBook--->CAS DataBase List--->1050500-41-8

1050500-41-8

1050500-41-8 Structure

1050500-41-8 Structure
IdentificationBack Directory
[Name]

PEG13-Tos
[CAS]

1050500-41-8
[Synonyms]

PEG13-Tos
PEG15-Tos
PEG12-Tos
Tos-PEG12-OH
35-hydroxy-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontyl 4-methylbenzenesulfonate
3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol, 1-(4-methylbenzenesulfonate)
[Molecular Formula]

C31H56O15S
[MDL Number]

MFCD28334511
[MOL File]

1050500-41-8.mol
[Molecular Weight]

700.83
Chemical PropertiesBack Directory
[Boiling point ]

724.4±60.0 °C(Predicted)
[density ]

1.166±0.06 g/cm3(Predicted)
[pka]

14.36±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Description]

PEG13-Tos is a PEG linker containing a hydroxyl group and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
[Uses]

PEG13-tos is a cross linker in the synthesis antibody-drug conjugates.
[IC 50]

Non-cleavable Linker; PEGs
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