| Identification | Back Directory | [Name]
GSK-2110183C | [CAS]
1047644-62-1 | [Synonyms]
Delitinib
Afuresertib
GSK2110183C
GSK-2110183C
GSK 2110183C
GSK-2110183C USP/EP/BP
GSK-2110183 Afuresertib
Afuresertib(GSK2110183C)
Afuresertib, GSK-2110183, GSK-2110183B
N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide
2-Thiophenecarboxamide, N-[(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)- | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C18H17Cl2FN4OS | [MDL Number]
MFCD26961098 | [MOL File]
1047644-62-1.mol | [Molecular Weight]
427.32 |
| Chemical Properties | Back Directory | [Boiling point ]
535.1±50.0 °C(Predicted) | [density ]
1.49±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C, protect from light, stored under nitrogen | [solubility ]
DMSO:62.5(Max Conc. mg/mL);146.26(Max Conc. mM)
Ethanol:85.0(Max Conc. mg/mL);198.91(Max Conc. mM) | [form ]
Powder | [pka]
13.03±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Afuresertib is a potent pan-AKT inhibitor that demonstrated synergy with bortezomib in preclinical models of multiple myeloma. | [Definition]
ChEBI: N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methyl-3-pyrazolyl)-2-thiophenecarboxamide is a member of amphetamines. | [storage]
Store at -20°C, protect from light, stored under nitrogen |
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