| Identification | Back Directory | [Name]
DEVAZEPIDE | [CAS]
103420-77-5 | [Synonyms]
MK-329
L-364718
DEVAZEPIDE
EVAZEPIDE, PANOS
(3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide
N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE
1H-Indole-2-carboxamide, N-[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]- | [Molecular Formula]
C25H20N4O2 | [MDL Number]
MFCD00864500 | [MOL File]
103420-77-5.mol | [Molecular Weight]
408.45 |
| Chemical Properties | Back Directory | [Boiling point ]
758.6±60.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: >5mg/mL | [form ]
powder | [pka]
13.25±0.40(Predicted) | [color ]
white to off-white |
| Hazard Information | Back Directory | [Uses]
Antagonist (cholecystokinin). | [Definition]
ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f
r treatment of gastrointestinal disorders. | [General Description]
Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone. | [Biochem/physiol Actions]
Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist. | [storage]
Store at +4°C |
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