| Identification | More | [Name]
FMOC-S-trityl-L-cysteine | [CAS]
103213-32-7 | [Synonyms]
2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-3-(TRITYLTHIO)PROPANOIC ACID
9-FLUORENYLMETHOXYCARBONYL-S-TRITYL-L-CYSTEINE
FMOC-CYSTEINE(TRT)-OH
FMOC-CYS(TRT)
FMOC-CYS(TRT)-OH
FMOC-L-CYSTEINE(TRITYL)
FMOC-L-CYSTEINE (TRT)
FMOC-L-CYS(TRITYL)
FMOC-L-CYS(TRT)
FMOC-L-CYS(TRT)-OH
FMOC-S-TRITYL-L-CYSTEINE
N-(9-FLUORENYL METHOXY CARBONYL)-S-TRITYL-L-CYSTEINE
N-9-FLUORENYLMETHYLOXYCARBONYL-S-TRITYL-L-CYSTEINE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-L-CYSTEINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-S-TRITYL-L-CYSTEINE
N-ALPHA-FMOC-S-TRITYL-L-CYSTEINE
N-FMOC-L-CYS(TRT)-OH
N-FMOC-S-TRITYL-L-CYSTEINE
(R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-TRITYLSULFANYL-PROPIONIC ACID
S-TRITYL-L-CYSTEINE, N-FMOC PROTECTED | [EINECS(EC#)]
600-408-4 | [Molecular Formula]
C37H31NO4S | [MDL Number]
MFCD00038538 | [Molecular Weight]
585.71 | [MOL File]
103213-32-7.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystal powde | [Melting point ]
170-173 °C(lit.)
| [alpha ]
16 º (c=1, THF) | [Boiling point ]
763.4±60.0 °C(Predicted) | [density ]
1.270±0.06 g/cm3(Predicted) | [refractive index ]
18 ° (C=1, THF) | [storage temp. ]
2-8°C
| [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Powder | [pka]
3.70±0.10(Predicted) | [color ]
White to almost white | [optical activity]
[α]20/D +16.0±2°, c = 1% in THF | [Water Solubility ]
Insoluble in water. Soluble in most organic solvents. | [Detection Methods]
T,NMR,Rotation | [BRN ]
4221286 | [InChIKey]
KLBPUVPNPAJWHZ-UMSFTDKQSA-N | [CAS DataBase Reference]
103213-32-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
9-21 | [Hazard Note ]
Irritant | [HS Code ]
29309099 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystal powde | [Uses]
It is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function. | [General Description]
The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP?, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.
The product number for this product was previously 04-12-1018.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”. | [reaction suitability]
reaction type: Fmoc solid-phase peptide synthesis |
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