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ChemicalBook--->CAS DataBase List--->103-86-6

103-86-6

103-86-6 Structure

103-86-6 Structure
IdentificationBack Directory
[Name]

4-(2-aminopropyl)phenol
[CAS]

103-86-6
[Synonyms]

Norpholedrine
p-Hydroxyamphetamine
.alpha.-Methyltyramine
4-(2-aminopropyl)phenol
Phenol,4-(2-aminopropyl)-
Dl-p-(2-aminopropyl)phenol
1-p-Hydroxyphenyl-2-propylamine
2-Amino-1-(p-hydroxyphenyl)propane
4-Hydroxy-.alpha.-methylphenethylamine
2-(4-Hydroxyphenyl)-1-methylethylamine
[EINECS(EC#)]

203-152-8
[Molecular Formula]

C9H13NO
[MDL Number]

MFCD00599960
[MOL File]

103-86-6.mol
[Molecular Weight]

151.206
Chemical PropertiesBack Directory
[Melting point ]

125-126 °C
[Boiling point ]

279.2±15.0 °C(Predicted)
[density ]

1.070±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

9.83±0.15(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS05
[Signal word ]

Danger
[Hazard statements ]

H318-H315-H302-H335
[Precautionary statements ]

P264-P270-P301+P312-P330-P501-P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
[Toxicity]

LDLo intravenous in rat: 100mg/kg
Hazard InformationBack Directory
[Uses]

p-Hydroxyamphetamine is a major metabolite of Amphetamine (A634240), a sympathomimetic and psychotropic drug which is extensively metabolized in liver and in brain.
[Definition]

ChEBI: 4-(2-aminopropyl)phenol is a member of amphetamines.
[Purification Methods]

Crystallise the phenol from *benzene. The R-(-)-enantiomer crystallises from EtOH or *C6H6 with m 110.5-111.5o and []17 -52.0o (c 1, EtOH). The (±)-hydrochloride has m 171-172o (EtOH/Et2O), and the 2,4-dinitrophenylhydrazone has m 190-192o (EtOH). [Beilstein 13 I 251, 13 III 1709, 13 IV 1871.]
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