Identification | Back Directory | [Name]
SODIUM PHENOTHIAZINE-10-YL-PROPYLSULFONATE | [CAS]
101199-38-6 | [Synonyms]
PTZ-343 PTZ 343;PTZ343 phenothiazine sodium salt sodiuM 3-(phenothiazin-10-yl)pro 3-(phenothiazin-10-yl)propane-1-sulfonate sodiuM 3-(phenothiazin-10-yl)propane-1-sulfonate Sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate 10H-Phenothiazine-10-propanesulfonic acid sodium salt 10H-Phenothiazine-10-propanesulfonic acid, sodiuM salt (1:1) | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C15H14NNaO3S2 | [MDL Number]
MFCD08275674 | [MOL File]
101199-38-6.mol | [Molecular Weight]
343.4 |
Chemical Properties | Back Directory | [Melting point ]
>232°C (dec.) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly, Heated) | [form ]
Solid | [color ]
Off-White to Pale Yellow | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C15H15NO3S2.Na.H/c17-21(18,19)11-5-10-16-12-6-1-3-8-14(12)20-15-9-4-2-7-13(15)16;;/h1-4,6-9H,5,10-11H2,(H,17,18,19);; | [InChIKey]
LAXVHQHEZUKIAE-UHFFFAOYSA-N | [SMILES]
C(N1C2=CC=CC=C2SC2C=CC=CC1=2)CCS(O)(=O)=O.[NaH] |
Hazard Information | Back Directory | [Description]
PTZ-343 is a phenothiazine (PTZ) derivative with chemical name sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate. The free acid of PTZ-343 has molecule weight 343. For the convenience of commucation, we call it as PTZ-343. PTZ-343 is a water-soluble enhancer of luminol chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP). It acts as an electron transfer mediator, reacting with HRP-II to release HRP and a PTZ-343 radical, which oxidizes luminol anions to induce light emission. | [Uses]
Sodium 3-?(10H-?Phenothiazin-?10-?yl)?propane-?1-?sulfonate can be used in biological and analytical studies of a portable chemiluminescence imaging immunoassay for simultaneous detection of different isoforms of prostate specific antigen in serum. | [in vitro]
PTZ-343 behaves as electron transfer mediator, it reacts with HRP-II to release HRP and a enhance (PTZ-343) radical. The enhancer (PTZ-343) radical quickly oxidizes luminol anions to induce light emission.
| [storage]
Store at -20°C,protect from light |
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