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ChemicalBook--->CAS DataBase List--->1002342-83-7

1002342-83-7

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          1002342-83-7 Structure
          
                                
          
                                1002342-83-7 Structure
                            
          
                                  		
                    
          
                
          
                
          IdentificationBack Directory
          [Name]

          Ald-PEG3-Azide
          [CAS]

          1002342-83-7
          [Synonyms]

          1002342-83-7
          Ald-PEG3-Azide
          CHO-PEG3-azide
          N3-PEG3-CH2CHO
          Ald-CH2-PEG3-N3
          ALD-CH2-PEG3-AZIDE
          [Molecular Formula]

          C8H15N3O4
          [MDL Number]

          MFCD24453193
          [MOL File]

          1002342-83-7.mol
          [Molecular Weight]

          217.23
          Chemical PropertiesBack Directory
          [solubility ]

          Soluble in Water, DMSO, DMF, DCM
          Hazard InformationBack Directory
          [Description]

          Ald-CH2-PEG3-azide is a click chemistry PEG linker. Aldehyde groups are likely to undergo nucleophile substitution, reduction and oxidation reactions. The azideN3 enable Click Chemistry reactions with alkynes, DBCO and BCN to form triazole groups. PEG3 spacer increases the water solubility of the compound.
          [Biological Activity]

          Ald-CH2-PEG3-azide is a cleavable 3-unit PEG-containing ADC linker that can be used to synthesize antibody drug conjugates (ADCs),it is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
          [in vitro]

           
           ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. 
           
             
          [target]

           
           
            Cleavable  
           
             
                     		  
            PEGs  
           
             
           
          
                      		
            
            
                
                
          
                    
                        
          
                            
                                
                                
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                        Tags:1002342-83-7
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