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ChemicalBook--->CAS DataBase List--->1002342-83-7

1002342-83-7

 
        

            

                

                    

                        
                            
                        
                        
                            

                                
1002342-83-7 Structure

                                

                                1002342-83-7 Structure
                            

                        		
                    

                

                
IdentificationBack Directory
[Name]

Ald-PEG3-Azide
[CAS]

1002342-83-7
[Synonyms]

1002342-83-7
Ald-PEG3-Azide
CHO-PEG3-azide
N3-PEG3-CH2CHO
Ald-CH2-PEG3-N3
ALD-CH2-PEG3-AZIDE
[Molecular Formula]

C8H15N3O4
[MDL Number]

MFCD24453193
[MOL File]

1002342-83-7.mol
[Molecular Weight]

217.23
Chemical PropertiesBack Directory
[solubility ]

Soluble in Water, DMSO, DMF, DCM
Hazard InformationBack Directory
[Description]

Ald-CH2-PEG3-azide is a click chemistry PEG linker. Aldehyde groups are likely to undergo nucleophile substitution, reduction and oxidation reactions. The azideN3 enable Click Chemistry reactions with alkynes, DBCO and BCN to form triazole groups. PEG3 spacer increases the water solubility of the compound.
[Biological Activity]

Ald-CH2-PEG3-azide is a cleavable 3-unit PEG-containing ADC linker that can be used to synthesize antibody drug conjugates (ADCs),it is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
[in vitro]

 
 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. 
 
   
[target]

 
 
  Cleavable  
 
   
 		  
  PEGs  
 
   
 

            		
            
            
                
                

                    
                        

                            
                                
                                
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