Many of the purine pyrimidine nucleoside analogues, which are promising antiviral compounds, are antiviral in tissue culture and in vivo. The compounds with selective inhibition of the virus, low toxicity, and effective in animals develop into nuclei Glycosides antiviral drugs.
2'-C-Methyluridine：a modified nucleoside
2'-C-Methyluridine, a modified nucleoside, crucial for RNA studies and therapeutics. Synthesis involves regioselective deprotectionand applications range from
Dec 15，2023 Nucleoside Drugs
β-Nicotinamide adenine dinucleotide: Biosynthesis, physiological function and application
β-Nicotinamide adenine dinucleotide is a cofactor and plays a major role in metabolism, involved in redox reactions, carrying electrons from one reaction to another.
Apr 17，2023 Nucleoside Drugs
Pseudouridine: Application and Pharmacology, Synthesis, Toxicity and safety
Pseudouridine (Ψ；5-ribosyluracil) is a C-glycosyl pyrimidine that consists of uracil having a beta-D-ribofuranosyl residue attached at position 5.
Mar 27，2023 Nucleoside Drugs
Cytidine 5′-Diphosphocholine (CDP-Choline) in Stroke and Other CNS Disorders
Citicoline is a brain chemical that occurs naturally in the body. As a medicine, it is taken by mouth as a supplement or given as an injection into the vein (by IV) or as a shot into the muscle.
Apr 12，2022 Nucleoside DrugsPreparation of Nicotinamide Riboside
Nicotinamide riboside (NR) naturally occurs in yeast, bacteria, and mammals. Therefore, often, nicotinamide riboside is produced biotechnologically from yeast.
Dec 28，2021 Nucleoside Drugs
What is Diethyl chlorothiophosphate?
Dimethyl chlorothiophosphate is a chemical that is used as an intermediate in the manufacture of pesticides and plasticisers. It is an organophosphate with sulfur and chlorine also bonded to the centr
Jan 16，2020 Nucleoside Drugs
Medical applications of 2'-C-methyluridine
2′-C-methyluridine is one of the key intermediates in the synthesis of nucleoside anti-hepatitis C and anti-leukemia drugs. There are two main applications of 2'-C-methyluridine, which are targeted at
Dec 9，2019 Nucleoside Drugs