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ChemicalBook CAS DataBase List Tetrabutylammonium bromide
1643-19-2

Tetrabutylammonium bromide synthesis

7synthesis methods
-

Yield:1643-19-2 98.9%

Reaction Conditions:

in acetonitrile at 82; for 33 h;Menshutkin Reaction;Solvent;Temperature;

Steps:



there,We experimented by increasing the amount based on optimal choice of reagent. Tributylamine (100 g, 0.54 mol) was added to a 500 mL eggplant-shaped flask equipped with a reflux condenser,And acetonitrile (100 g) were added,here,1.1 equivalents (81.4 g, 0.6 mol equivalent)Of 1-bromobutane. Maintained at 82 ° C in an oil bath and reacted with stirring for 33 hours. The solution after reaction showed a slight yellow color. From this, acetonitrile was distilled off by an evaporator to obtain a pale orange solid. The solid was appropriately washed with suction filtration with ethyl acetate and dried. The yellow solution immediately after the reaction was analyzed by NMR,99.5% of tributylamine was reacting. Incidentally,0.5% of tributylamine remained.After washing with ethyl acetate, white tetrabutylammonium bromide was obtained.The yield of this was 98.9%The purity was 100%.

References:

JP2016/44149,2016,A Location in patent:Paragraph 0065

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