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ChemicalBook CAS DataBase List TERT-BUTYL PROPIOLATE
13831-03-3

TERT-BUTYL PROPIOLATE synthesis

3synthesis methods
-

Yield:13831-03-3 80 g

Reaction Conditions:

with dmap;dicyclohexyl-carbodiimide in tetrahydrofuran for 24 h;

Steps:

7 Synthesis of Compound 18
Approximately 60g of compound 17 (propiolic acid), N of about 100 g, N'-dicyclohexylcarbodiimide (N, N'-dicyclohexylcarbodiimide), about 10g of 4- (dimethylamino) pyridine (4- (dimethylamino ) pyridine)), and about 20g of tert- butanol (tert-butanol), it was dissolved in tetrahydrofuran and stirred for about 24 hours.After extraction with dichloromethane and water, the extracted organic layer was chemically dried and purified by column chromatography to give compound 18 of about 80 g.

References:

LG Chem Limited;Min Hyung, Lee;Yong Ji, Son;Sung-Ho, Chun;Kyung Chang, Seo;Hyeong Bin, Jang;Ji Yong, Choe JP2016/533394, 2016, A Location in patent:Paragraph 0103

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