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ChemicalBook CAS DataBase List (S)-(-)-1-Phenylethyl isocyanate
14649-03-7

(S)-(-)-1-Phenylethyl isocyanate synthesis

3synthesis methods
-

Yield:-

Reaction Conditions:

in toluene for 4 h;Reflux;

Steps:

13.1 Preparation of Compound 13:
Step 1, benzylamine (5 mmol, 600 mg) and toluene (10 mL) were added to a 100 mL round bottom flask, and triphosgene (5 mmol, 1.5 g) was added under stirring, and the reaction was refluxed for 4 hours. The solvent was removed by concentration, then dichloromethane (5 mL) was evaporated.

References:

Chengdu Lianchuang Rongcheng Pharmaceutical Technology Co., Ltd.;Zhang Hongyan;Ye Xin;Wang Min CN108409614, 2018, A Location in patent:Paragraph 0173-0176

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