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590371-88-3

Quinoline, 8-bromo-2-chloro-3-iodo- synthesis

4synthesis methods
71910-51-5 Synthesis
N-(2-BROMOPHENYL)-3-PHENYLPROP-2-ENAMIDE

71910-51-5
50 suppliers
$28.60/50mg

Quinoline, 8-bromo-2-chloro-3-iodo-

590371-88-3
18 suppliers
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: 56 percent / aluminium chloride / chlorobenzene / 2 h / 125 °C
2: 83 percent / phosphorus oxychloride / 2 h / 125 °C
3: 79 percent / diisopropylamine; butyllithium; iodine / tetrahydrofuran; hexane / 2 h / -75 °C

References:

Cottet, Fabrice;Marull, Marc;Lefebvre, Olivier;Schlosser, Manfred [European Journal of Organic Chemistry,2003,# 8,p. 1559 - 1568]