PYRIDINE, 2-CHLORO-5-(PHENYLMETHOXY)- synthesis
- Product Name:PYRIDINE, 2-CHLORO-5-(PHENYLMETHOXY)-
- CAS Number:84611-43-8
- Molecular formula:C12H10ClNO
- Molecular Weight:219.67
41288-96-4
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100-39-0
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84611-43-8
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$45.00/50mg
Yield:84611-43-8 100%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 60; for 18 h;
Steps:
166-1 (166-1) Synthesis of 5- (benzyloxy) -2-chloropyridine (Compound 166-1)
6-chloropyridin-3-ol (1.0 g),Benzyl bromide (1.5 g) and potassium carbonate (2.4 g)Was dissolved in DMF (40 mL) and stirred at 60 ° C. for 18 hours.After filtering the reaction solution,The solvent of the obtained filtrate was distilled off under reduced pressure to obtain a residue,Purification by silica gel column chromatography (hexane-ethyl acetate)5- (benzyloxy) -2-chloropyridine1.3 g (yield quant.) Was obtained.
References:
JP2017/171619,2017,A Location in patent:Paragraph 0233; 0235
41288-96-4
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$8.00/1g
100-44-7
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84611-43-8
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$45.00/50mg
69045-79-0
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100-51-6
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84611-43-8
48 suppliers
$45.00/50mg
53939-30-3
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$5.00/1g
100-51-6
1429 suppliers
$5.00/100g
84611-43-8
48 suppliers
$45.00/50mg
100-39-0
439 suppliers
$10.00/10g
84611-43-8
48 suppliers
$45.00/50mg