ChemicalBook CAS DataBase List POTASSIUM GLYCOLATE

POTASSIUM GLYCOLATE synthesis

6synthesis methods

Product Name:POTASSIUM GLYCOLATE
CAS Number:1932-50-9
Molecular formula:C2H3KO3
Molecular Weight:114.14

79-14-1 Synthesis

79-14-1
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1932-50-9
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Yield:-

Reaction Conditions:

with potassium hydroxide in water at 40; for 0.5 h;Reagent/catalyst;Temperature;

Steps:

2
Weigh 113.0g of 70% glycolic acid(1.04 mol) aqueous solution,Slowly add at 40 ° C116.7 g of 50% potassium hydroxide (1.04 mol),After the addition is completed, the temperature is kept at this temperature for 0.5 h.After the reaction is completed, the reaction solution is evaporated to dryness under reduced pressure to ≤0.3%.Potassium glycolate is used.Add to the prepared potassium glycolate252.5 g of 30% potassium methoxide (1.08 mol) in methanol,The reaction was kept at 20 ° C for 1 h with stirring.A solution of dipotassium glycolate in methanol is obtained.0.72 g of cetyltrimethylammonium bromide was added thereto.Add 183.8 g of 99% 1,2,4-trichlorobenzene (1 mol),The temperature was raised to 40 ° C for 3 h.The reaction is completed,Methanol is recovered by distillation under reduced pressure.Add 300g of water,Warming up to 40 ° C,Add 30% hydrochloric acid to a pH of 0.2,Cool down to room temperature,Drying 2,4-dichlorophenoxyacetic acid 217.9g,The content is 98.4%,The total reaction yield was 97.9% based on 1,2,4-trichlorobenzene.

References:

Shandong Runbo Biological Technology Co., Ltd.;Sun Guoqing;Hou Yongsheng;Zhang Liguo;Zhao Guangli;Chen Guiyuan CN108503524, 2018, A Location in patent:Paragraph 0040; 0041; 0042; 0043

107-21-1 Synthesis