Phenol, 2-(1-aminoethyl)-4-methoxy-, (S)- (9CI) synthesis
1synthesis methods
- Product Name:Phenol, 2-(1-aminoethyl)-4-methoxy-, (S)- (9CI)
- CAS Number:180683-46-9
- Molecular formula:C9H13NO2
- Molecular Weight:167.21
Yield:-
Reaction Conditions:
with (S)-3,3'-bis(triphenylsilyl)-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate;di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate in benzene at 50; for 72 h;Inert atmosphere;optical yield given as %ee;enantioselective reaction;
References:
Nguyen, Thanh Binh;Bousserouel, Hadjira;Wang, Qian;Gueritte, Francoise [Organic Letters,2010,vol. 12,# 20,p. 4705 - 4707] Location in patent:supporting information; experimental part