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90736-23-5

p-Fluoro Fentanyl synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1) p-toluenesulfonic acid monohydrate, 2) NaBH4 / 1) toluene, 22 h, reflux, 2) ethanol, rt, 3 h
2: toluene / 3 h / Heating

References:

Brine;Boldt;Huang;Sawyer;Carroll [Journal of Heterocyclic Chemistry,1989,vol. 26,# 3,p. 677 - 686]

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