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139-61-7

P-CYCLOHEXYLOXYBENZOIC ACID synthesis

8synthesis methods
-

Yield:139-61-7 68%

Reaction Conditions:

Stage #1: Ethyl 4-hydroxybenzoate;cyclohexenewith boron trifluoride diethyl etherate for 2 h;Inert atmosphere;Reflux;
Stage #2: with sodium hydroxide in methanol;water;acetone; for 3 h;Inert atmosphere;Reflux;

References:

Kloss, Florian;Lincke, Thorger;Hertweck, Christian [European Journal of Organic Chemistry,2011,# 8,p. 1429 - 1431] Location in patent:supporting information; experimental part

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