N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE synthesis
- Product Name:N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE
- CAS Number:3070-86-8
- Molecular formula:C16H16N2O3
- Molecular Weight:284.31
108-24-7
5 suppliers
$14.00/250ML
101-80-4
502 suppliers
$6.00/25g
3070-86-8
72 suppliers
$54.00/100mg
Yield: 98%
Reaction Conditions:
in acetone at 0;
Steps:
1.2. General Procedure for the Synthesis of Substituted Compounds 8-15
To a stirred acetone (50 ml) solution of 4, 4′-diaminodiphenyl ether (2) (5.0 g, 19.6 mmol) at 0 °C, acetic anhydride (10.0 ml, 105.8 mmol) was added dropwise and reaction had been carried out for 3 h. The reaction was monitored by TLC. After stopping the reaction, triethylamine (25 ml, 179.4 mmol) was added dropwise, neutralizing the solution, to give a white solid, filtrated, washed with acetone, and dried to obtain the compound 3.
References:
Wang, Xiu-Jun;Chu, Na-Ying;Wang, Qin-He;Liu, Chao;Jiang, Chun-Guo;Wang, Xiao-Yu;Ikejima, Takashi;Cheng, Mao-Sheng [Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,# 19,p. 6297 - 6300] Location in patent:supporting information
100-00-5
12 suppliers
$14.00/25g
3070-86-8
72 suppliers
$54.00/100mg
101-63-3
110 suppliers
$10.00/1g
3070-86-8
72 suppliers
$54.00/100mg
100-02-7
19 suppliers
$11.00/5G
3070-86-8
72 suppliers
$54.00/100mg
103-90-2
1053 suppliers
$9.00/1g
3070-86-8
72 suppliers
$54.00/100mg