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ChemicalBook CAS DataBase List N-HYDROXYBUTYRAMIDINE
27620-10-6

N-HYDROXYBUTYRAMIDINE synthesis

1synthesis methods

A solution of a mixture of butyronitrile, NaOH and hydroxylamine hydrochloride in 95% ethanol and water was refluxed Heat for 12 hours. The solvent was removed in vacuo, the oily residue was dissolved in chloroform , and insoluble NaCl was removed by filtration. The filtrate was concentrated in vacuo to give N-hydroxybutyramidine as a colorless oil.

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Yield:27620-10-6 72%

Reaction Conditions:

with hydroxylamine hydrochloride;sodium carbonate in ethanol;water at 55; for 0.5 h;Sonication;

References:

Barros, Carlos Jonnatan Pimentel;De Freitas, Jucleiton J. Rufino;De Oliveira, Ronaldo N.;De Freitas Filho, Jo?o R. [Journal of the Chilean Chemical Society,2011,vol. 56,# 2,p. 721 - 722] Location in patent:experimental part

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