ChemicalBook CAS DataBase List N-(2,4-dimethyl-6-nitro-phenyl)acetamide

N-(2,4-dimethyl-6-nitro-phenyl)acetamide synthesis

4synthesis methods

Product Name:N-(2,4-dimethyl-6-nitro-phenyl)acetamide
CAS Number:606-38-2
Molecular formula:C10H12N2O3
Molecular Weight:208.21

2050-43-3
59 suppliers
$15.00/5mg

N-(2,4-dimethyl-6-nitro-phenyl)acetamide

606-38-2
26 suppliers
$15.00/5mg

Yield:606-38-2 93%

Reaction Conditions:

with ammonium nitrate;sulfuric acid;glacial acetic acid at 15 - 30; for 2 h;Temperature;

Steps:

1-3 Example 1

Add 135g 2,4-dinitroacetanilide, 800g acetic acid to a 1000ml three-necked reaction flask, start stirring, add 78.9g (1.20eq) ammonium nitrate, control the temperature at 15-30°C, add 99.0g 98% concentrated sulfuric acid dropwise, dropwise After adding 98% concentrated sulfuric acid, react for 2 hours, add 1000.0g purified water in a 2000ml three-necked flask after the reaction is completed, control the temperature at 1020°C, transfer the reaction solution into the above purified water, stir for 0.51 hour , filtered, the filter cake was slurried with water, and dried to obtain 160.2 g of solid 4-acetamido-5-nitro-m-xylene with a yield of 93.0% and a purity of 92.8%.

References:

CN114621111,2022,A Location in patent:Paragraph 0017; 0019-0026

2050-43-3
59 suppliers
$15.00/5mg

606-38-2
26 suppliers
$15.00/5mg