ChemicalBook CAS DataBase List METHYL PERFLUOROOCTANOATE

METHYL PERFLUOROOCTANOATE synthesis

11synthesis methods

Product Name:METHYL PERFLUOROOCTANOATE
CAS Number:376-27-2
Molecular formula:C9H3F15O2
Molecular Weight:428.1

67-56-1 Synthesis

67-56-1
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335-67-1
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$10.00/1 g

376-27-2
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$10.00/2 g

Yield:376-27-2 89%

Reaction Conditions:

with sulfuric acid for 4 h;Heating / reflux;

Steps:

2.i
EXAMPLE 2; Synthesis of perfluoro-N¹ , N⁷ -dioctanimidoylheptanediimidamide (DPIA-56); (i) Methyl perfluorooctanoate; A 2-1, four-necked, round-bottomed flask equipped with stirrer, addition funnel, thermometer and reflux condenser, is charged with 828 g (2 mol) of dried perfluorooctanoic acid, 16O g (5 mol) of methanol. The mixture is stirred and 50 ml concentrated sulfuric acid is added dropwise. Then the mixture is heated to reflux for 4 hr. At the end of the reflux period the mixture is cooled to room temperature and poured into 2 1 cold water. After separation of the phases, the lower organic phase is washed with water till pH neutral and dried over CaCl₂. Distillation of the crude gives 762 g (89%) of methyl perfluorooctanoate, bp 160⁰C.

References:

LODESTAR INC. WO2008/8316, 2008, A2 Location in patent:Page/Page column 29-30

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111-11-5 Synthesis