Methyl 3-mercaptopropionate synthesis
- Product Name:Methyl 3-mercaptopropionate
- CAS Number:2935-90-2
- Molecular formula:C4H8O2S
- Molecular Weight:120.17
Yield:2935-90-2 94.6%
Reaction Conditions:
with 1-methyl-3-(3-sulfopropyl)imidazol-3-ium hydrogen sulfate at 50; for 0.00277778 h;Catalytic behavior;Flow reactor;Large scale;Temperature;
Steps:
1 Example 1
Weigh 1810 g of methanol, 2000 g of 3-mercaptopropionic acid, and 100 g of catalyst, mix 3-mercaptopropionic acid and catalyst evenly, and pump methanol, 3-mercaptopropionic acid, and catalyst solution into the microchannel reactor respectively, at 50° C. The reaction was carried out, the feeding speed of the pump was adjusted, the molar ratio of 3-mercaptopropionic acid and methanol was controlled to be 1:3, and the residence time was 10 seconds.After receiving the reaction material, the liquid was left to stand for stratification, and the upper reaction liquid was distilled and separated to obtain 2139.9 g of methyl 3-mercaptopropionate, and the calculated yield was 94.6%.The mass of the lower ionic liquid after dehydration is 210 g, and the content of mercaptopropionic acid is 51.4% in quantitative analysis.
References:
CN114773241,2022,A Location in patent:Paragraph 0018-0021
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