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ChemicalBook CAS DataBase List Methyl 3,4-diaminobenzoate
36692-49-6

Methyl 3,4-diaminobenzoate synthesis

9synthesis methods
-

Yield:36692-49-6 98.1%

Reaction Conditions:

with sulfuric acid at 90; for 12 h;Temperature;

Steps:

1.1; 2.1; 3.1; 4.1; 5.1; 6.1 (1)Synthesis of methyl 3,4-diaminobenzoate (2)

Take a 100 ml single-mouth bottle, add 3,4-diaminobenzoic acid (1) 3.04 g (0.02 mol), and add 50 mL of methanol.Stir and dissolve, then add 19.6 g (0.2 mol) of concentrated sulfuric acid.Stir at 90 ° C for 12 hours. After the reaction is completed,Methanol is distilled off under reduced pressure, and the residue is poured into ice water.Drying by suction filtration to obtain methyl 3,4-diaminobenzoate (2)3.26g,The yield was 98.1%.

References:

CN108997229,2018,A Location in patent:Paragraph 0015; 0025; 0028; 0031; 0034; 0037

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