M-(2-Methoxyethyl)phenol synthesis
- Product Name:M-(2-Methoxyethyl)phenol
- CAS Number:32846-01-8
- Molecular formula:C9H12O2
- Molecular Weight:152.19
4009-98-7
354 suppliers
$5.00/10g
100-83-4
635 suppliers
$5.00/10g
32846-01-8
24 suppliers
$278.00/100mg
Yield:32846-01-8 90%
Reaction Conditions:
Stage #1: (methoxymethyl)triphenylphosphonium chloridewith potassium tert-butylate in tetrahydrofuran at 0; for 1 h;
Stage #2: meta-hydroxybenzaldehyde in tetrahydrofuran at 20; for 7 h;
References:
Tahirovic, Yesim A.;Geballe, Matthew;Gruszecka-Kowalik, Ewa;Myers, Scott J.;Lyuboslavsky, Polina;Le, Phuong;French, Adam;Irier, Hasan;Choi, Woo-Baeg;Easterling, Keith;Yuan, Hongjie;Wilson, Lawrence J.;Kotloski, Robert;McNamara, James O.;Dingledine, Raymond;Liotta, Dennis C.;Traynelis, Stephen F.;Snyder, James P. [Journal of Medicinal Chemistry,2008,vol. 51,# 18,p. 5506 - 5521] Location in patent:supporting information; experimental part