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ChemicalBook CAS DataBase List Isopropyl(4-chlorophenyl)acetyl chloride
51631-50-6

Isopropyl(4-chlorophenyl)acetyl chloride synthesis

3synthesis methods
Isopropyl(4-chlorophenyl)acetyl chloride can be obtained by chlorination of α-isopropyl p-chlorophenylacetic acid.
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Yield:-

Steps:

Multi-step reaction with 4 steps
1: 65 percent / ethanol; H2O
2: 50 percent / KOH, Tween-80 / xylene
3: 70 percent / H2SO4 / acetic acid; H2O
4: 100 percent / SOCl2 / benzene

References:

Volkov, Yu. P.;Kalinevich, V. M.;Trusova, E. I.;Bilevich, K. A.;Kryshtal', G. V.;Yanovskaya, L. Ya. [Bulletin of the Academy of Sciences of the USSR Division of Chemical Science,1986,vol. 35,# 6,p. 1239 - 1242][Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya,1986,# 6,p. 1365 - 1368]

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