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ChemicalBook CAS DataBase List Hexanoyl chloride
142-61-0

Hexanoyl chloride synthesis

13synthesis methods
-

Yield:142-61-0 97.8%

Reaction Conditions:

with thionyl chloride in toluene for 3 h;Reflux;

Steps:

1.1 (1) Preparation of n-hexanoyl chloride
In 250mL three-necked flask were added 11.6g (0.1mol) n-caproic acid and 100mL of toluene, was added dropwise 17.9g (0.15 mol) of thionyl chloride and 30mL of toluene was dropwise Bi, heated to reflux and the reaction stirred for 3h, spin The solvent was evaporated to remove toluene and thionyl chloride to give a pale yellow oily liquid 13.2g, a yield of 97.8%.

References:

Qingdao University of Science and Technology;Wang, Minghui;Xu, Liangzhong;Ju, Guangxiu;Chen, Gexin;Xu, Shanshan CN105669550, 2016, A Location in patent:Paragraph 0023; 0024; 0025

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