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ChemicalBook CAS DataBase List H-GLY-ALA-LEU-OH
22849-49-6

H-GLY-ALA-LEU-OH synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: diethyl phosphorocyanidate, TEA / dimethylformamide / 1.) 0 deg C; 2.) r.t.
2: H2 / 5percent Pd on charcoal / methanol / 10 h / Ambient temperature
3: diethyl phosphorocyanidate, TEA / dimethylformamide / 1.) 0 deg C; 2.) r.t.
4: TFA / 1 h / Ambient temperature

References:

Ikota, Nobuo;Shioiri, Takayuki;Yamada, Shun-Ichi [Chemical and pharmaceutical bulletin,1980,vol. 28,# 10,p. 3064 - 3069]

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