ChemicalBook CAS DataBase List Ethylhexylglycerin

Ethylhexylglycerin synthesis

6synthesis methods

Product Name:Ethylhexylglycerin
CAS Number:70445-33-9
Molecular formula:C11H24O3
Molecular Weight:204.31

Synthesis of ethylhexylglycerin is via the catalytic splitting of ethylhexylglycidyl ether followed by the addition of water. The product can then be purified by vacuum distillation.

104-76-7 Synthesis

104-76-7
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$5.00/10g

96-24-2
304 suppliers
$11.00/5g

70445-33-9
381 suppliers
$10.00/5g

Yield:70445-33-9 92.4%

Reaction Conditions:

with sodium hydroxide at 90; for 0.666667 h;Temperature;Reagent/catalyst;

Steps:

1-4 Example 4

Stir the sodium hydroxide and isooctanol in the pre-mixing tank 1 according to 1.5:1 (molar ratio), and then enter the first oil bath raw material storage tank 4 to preheat to 90°C, and add 3-chloro-1,2- Propylene glycol is preheated to 90°C in the second oil bath raw material storage tank 8.The above-mentioned two preheated raw materials were pumped into the micromixer 12 according to the flow volume ratio of 1:1.3, mixed, and then entered into the microchannel reactor 13 for reaction. The diameter of the microchannel reactor 13 was 2.0mm, and the reaction temperature was 90. , The reaction time is 40 minutes, and the crude ethylhexyl glycerol is obtained. The content of ethylhexyl glycerol in online GC analysis is 94.6%.Adjust the PH value of the crude product to 7 with hydrochloric acid solution, lower it to room temperature, separate the product from oil and water with a separatory funnel, drain the water phase, wash the organic phase twice with water, separate the organic phase, and pass the molecular distillation equipment in a vacuum The temperature is 40-50Pa, and 138±3°C fractions are collected to obtain ethylhexylglycerol as a colorless and transparent liquid. According to gas chromatography analysis, the purity of ethylhexylglycerol is 99.7%, and the yield is 92.4%.

References:

CN112661614,2021,A Location in patent:Paragraph 0026-0033

2461-15-6 Synthesis