ChemicalBook CAS DataBase List Ethyl L-alaninate hydrochloride

Ethyl L-alaninate hydrochloride synthesis

3synthesis methods

Product Name:Ethyl L-alaninate hydrochloride
CAS Number:1115-59-9
Molecular formula:C5H12ClNO2
Molecular Weight:153.61

56-41-7 Synthesis

56-41-7
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$5.00/5g

1115-59-9
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$13.50/5G

Yield:1115-59-9 98%

Reaction Conditions:

in ethanol

Steps:

1.a a)
a) L-Alanine ethyl ester hydrochloride (2) Hydrogen chloride gas was bubbled into a suspension of L-alanine (1) (100 g, 1.12 mol) in dry ethanol (800 ml) and the solution was refluxed for 2 hours. After concentration in vacuo the compound was recrystallized from ethanol-diethyl ether giving the title ester (2) (168.2g, 98%) as a white solid. δ_H (200 MHz; D₂ O) 1.11 (3H, t, J=7.1, CH₂ CH₃), 1.37 (3H, d, J=7.4, CHCH₃), 4.03 (1H, q, J=7.2, CHCH₃), 4.09 (2H, q, J=7.2, CH₂ CH₃), 4.16 (2H, s, NH₂); δ_C (125 MHz; D₂ O) 13.98 (CH₃), 15.90 (CH₃), 49.65 (CH), 64.29 (CH₂), 171.57 (CO).