ETHYL 8-OXO-8-PHENYLOCTANOATE synthesis
- Product Name:ETHYL 8-OXO-8-PHENYLOCTANOATE
- CAS Number:103187-95-7
- Molecular formula:C16H22O3
- Molecular Weight:262.34
Yield:103187-95-7 80%
Reaction Conditions:
Stage #1: ethyl 7-iodoheptanoatewith chloro-trimethyl-silane;zinc;1,1-dibromomethane in tetrahydrofuran at 20 - 60; for 16 h;
Stage #2: with lithium chloride in tetrahydrofuran at 0; for 0.166667 h;
Stage #3: benzoyl chloride in tetrahydrofuran at 0; for 3 h;Further stages.;
References:
Woo, Soon Hyung;Frechette, Sylvie;Khalil, Elie Abou;Bouchain, Giliane;Vaisburg, Arkadii;Bernstein, Naomy;Moradei, Oscar;Leit, Silvana;Allan, Martin;Fournel, Marielle;Trachy-Bourget, Marie-Claude;Li, Zuomei;Besterman, Jeffrey M.;Delorme, Daniel [Journal of Medicinal Chemistry,2002,vol. 45,# 13,p. 2877 - 2885]
29823-18-5
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103187-95-7
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