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ChemicalBook CAS DataBase List Dichloroacetyl chloride
79-36-7

Dichloroacetyl chloride synthesis

9synthesis methods
Dichloroacetyl chloride can be synthesized by the reaction of dichloroacetic acid and chlorosulfonic acid. Or from the oxidation of trichloroethylene. Trichloroethylene and azobisisobutyronitrile (catalyst) were heated to 100°C, and oxygen was introduced to react under 0.6MPa pressure, maintaining the oil bath temperature at 110°C, and reacted for 10h, The product dichloroacetyl chloride is distilled off under normal pressure.
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Yield:79-36-7 90%

Reaction Conditions:

with tributyl borane;oxygen at 80; under 2280.15 Torr; for 11 h;Reagent/catalyst;

Steps:

1.1; 2.1; 3.1

Add 1314g (10mol) of trichloroethylene and 18.2g (0.1mol) of tributylboron into the pressure-resistant reactor, then pass in dry oxygen, adjust the pressure of the oxygen to 3 atmospheres, and then increase the temperature React at 80°C for 11h. After the completion of the reaction, atmospheric distillation is performed, and the fractions are collected at a temperature range of 105°C to 108°C to obtain 1,325 g of a colorless and transparent liquid product, dichloroacetyl chloride, with a yield of 90%.

References:

CN111995516,2020,A Location in patent:Paragraph 0041; 0043-0044; 0058; 0060-0061; 0066; 0068-0069

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