ChemicalBook CAS DataBase List Dibenzyl phosphite

Dibenzyl phosphite synthesis

8synthesis methods

Product Name:Dibenzyl phosphite
CAS Number:17176-77-1
Molecular formula:C14H15O3P
Molecular Weight:262.24

868-85-9
278 suppliers
$25.00/5 g

100-51-6 Synthesis

100-51-6
1401 suppliers
$5.00/100g

17176-77-1
184 suppliers
$9.00/1g

Yield:17176-77-1 86.6%

Reaction Conditions:

with sodium methylate at 140; under 9.0009 Torr;Reflux;Inert atmosphere;

Steps:

5 Example 5
In a nitrogen-protected 1 L round bottom three-necked flask, 110 g of dimethyl phosphite, 325.2 g of benzyl alcohol, and 2.2 g of MeONa were added; the temperature was raised to reflux with stirring, and a fraction (methanol) of 60 to 65 ° C was collected, and then the bottom temperature of the kettle was set to 140 ° C. At 1.2kPa, the temperature was further increased to reflux, and the second stage fraction (excess benzyl alcohol) was distilled off, and the crude di (benzyl) phosphite was obtained at the bottom of the kettle; the crude dibenzyl phosphite was further washed with water, and 500 ml of It was extracted with methyl chloride, dried over anhydrous sodium sulfate, and after desolvation, 235.6 g of dibenzyl phosphite with a purity of 96.4% was obtained with a yield of 86.6%.

References:

Sichuan Fusida Bio-technology Development Co., Ltd.;Liu Hu;Yang Lu;Li Zhou;Wang Wen;Zhang Xian CN110669069, 2020, A Location in patent:Paragraph 0027

FullText

100-51-6 Synthesis

100-51-6
1401 suppliers
$5.00/100g

17176-77-1
184 suppliers
$9.00/1g

References