ChemicalBook CAS DataBase List DI-N-HEXYL SULFONE

DI-N-HEXYL SULFONE synthesis

4synthesis methods

Product Name:DI-N-HEXYL SULFONE
CAS Number:16823-61-3
Molecular formula:C12H26O2S
Molecular Weight:234.4

6294-31-1 Synthesis

6294-31-1
135 suppliers
$26.30/5g

16823-61-3
11 suppliers
inquiry

Yield:16823-61-3 99%

Reaction Conditions:

with phthalic anhydride;urea hydrogen peroxide adduct in ethyl acetate at 20;Green chemistry;

Steps:

Procedure B:

General procedure: To a solution of sulfide 1 (200 mg, 1-2 mmol, 1 equiv) in EtOAc (5 mL) was added UHP (3 equiv) and phthalic anhydride (3equiv) and the solution was allowed to stir for 12-16 h at r.t. The reaction was quenched with sat. aq Na2SO3 (10 mL) and then diluted withEtOAc (5 mL). The organics were washed with 1 N aq NaOH (2 × 10mL), H2O (10 mL), and brine (10 mL). The organics were dried (Na2-SO4) and concentrated to give the desired, spectroscopically pure sulfoneproduct.

References:

Lutz, Marlon;Wenzler, Marta;Likhotvorik, Igor [Synthesis,2018,vol. 50,# 11,p. 2231 - 2234] Location in patent:supporting information