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ChemicalBook CAS DataBase List Desmethylanhydroicaritin
28610-31-3

Desmethylanhydroicaritin synthesis

9synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 9 steps
1.1: potassium carbonate / acetone / 20 °C
2.1: potassium hydroxide / ethanol / 48 h / 20 °C
3.1: iodine / dimethyl sulfoxide / 24 h / Reflux
4.1: Oxone; sodium carbonate; sodium hydrogencarbonate / dichloromethane; acetone / 5 h / 0 °C
4.2: 0.5 h / 20 °C
5.1: hydrogenchloride / ethanol; water / 0.5 h / 20 °C
6.1: potassium carbonate / acetone / 0.5 h / 20 °C
6.2: 2 h / 20 °C
7.1: potassium carbonate / acetone / 1 h / 20 °C
7.2: 5 h / 50 °C
8.1: N,N-diethylaniline / 0.75 h / 190 °C / Microwave irradiation; Inert atmosphere
9.1: hydrogenchloride / water; methanol / 2 h / Reflux

References:

Nguyen, Van-Son;Dong, Lin-Pei;Wang, Sheng-Chun;Wang, Qiuan [European Journal of Organic Chemistry,2015,vol. 2015,# 10,p. 2297 - 2302]

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