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ChemicalBook CAS DataBase List Cyclobutene-1-carboxylic acid methyl ester
40628-41-9

Cyclobutene-1-carboxylic acid methyl ester synthesis

4synthesis methods
-

Yield:40628-41-9 85%

Reaction Conditions:

Stage #1: ethyl 1-bromocyclobutane-1-carboxylatewith potassium hydroxide in toluene;Heating;
Stage #2: methyl iodidewith N,N,N,N,N,N-hexamethylphosphoric triamide in water at 20; for 24 h;Further stages.;

References:

Chen, Xiao-Ping;Sufi, Bilal A.;Padias, Anne Buyle;Hall Jr. [Macromolecules,2002,vol. 35,# 11,p. 4277 - 4281]