成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

<dl id="szkjd"><dfn id="szkjd"></dfn></dl>
<button id="szkjd"><input id="szkjd"></input></button>
  • <thead id="szkjd"><strike id="szkjd"><li id="szkjd"></li></strike></thead>
    <tfoot id="szkjd"><output id="szkjd"><center id="szkjd"></center></output></tfoot>
    <form id="szkjd"><thead id="szkjd"><sub id="szkjd"></sub></thead></form><center id="szkjd"></center>
    <ins id="szkjd"><label id="szkjd"><nobr id="szkjd"></nobr></label></ins>
    • 
    
    
    
    
	    
    Welcome to chemicalbook!
    
  	    
    
          Chinese
          English
          Japanese
          Germany
          Korea
          
        
          
    
          
    400-158-6606
    
      
    
 
    
    
    

    


    


    

	

    
            
            




    

    
    
    
    
    
        
    
            
            
    
                Try our best to find the right business for you.
                
            
    
        
    
        
    
            
            
    
                
                
    
                    Do not miss inquiry messages
                    Please log in to view all inquiry messages.
            
                
    
                
            
    
        
    

        
    
            
            
    
                
                
    
                    
    Welcome back!
    
                    
                
    
                
            
    
        
    

    
    


    

    


    
    
    











    
    
    
    
        
    
    
    
    
        
        ChemicalBook
        CAS DataBase List
        Chenodeoxycholic acid
        
    
    
    
    
        
    
            
    
                474-25-9
            
    
        
    
        
    
            Chenodeoxycholic acid synthesis
        
    
        
    8synthesis methods
    
        
    
    

    
    
    
        
        
    
            
            
            
            
    
                -
            
    
            
    
                
                
    Yield:474-25-9 97% 
    
                
                
    Reaction Conditions:
    
                
    with water;sodium hydroxide in methanol; for 1 h;Reflux;
    
                
                
    Steps:
    
                
    
                    2.2.9. 2β, 3, 6α-Trihydroxyl-5β-cholanoate (H9/H10)

    General procedure: To a stirred solution of compound H8 (3α)(0.1011g, 0.2mmol) in MeOH (4mL) and H2O (1mL) was added NaOH (0.0441g, 1.1mmol) at room temperature. The mixture was heated at reflux for 1h, and then adjusted to pH 1-2 with 1M HCl aq to afford compound 2β, 3α, 6α-trihydroxyl-5β-cholanoate H9 (0.0794g, 90% yield) as white solid; mp 52-55°C; (α)20D αD20 =-9.2 (c=0.5, CH2Cl2); FTIR (KBr, cm-1) 3443 (O-H), 1704 (C=O), 1025 and 1023 (C-O); HRMS (ESI, m/z) Calcd for C24H40O5 408.2876; found: 431.2751 [M+Na]+ (Calcd 431.2773). H9 1H NMR (600MHz, CD3OD) δ 4.08 (dt, J=11.1, 4.2Hz, 1H, 6β-H), 4.02-3.96 (m, 1H, 2α-H), 3.68-3.61 (m, 1H, 3β-H), 1.00 (s, 3H, 19-H), 0.98 (d, J=6.5Hz, 3H, 21-H), 0.72 (s, 3H, 18-H); 13C NMR (151MHz, CD3OD) δ 176.7 (C-24), 68.9 (C-3), 67.1 (C-6), 67.0 (C-2), 56.1, 55.9, 42.6, 42.1, 40.4, 39.9, 37.8, 37.7, 35.3, 34.8, 33.9, 30.9, 30.6, 27.8, 25.5, 23.8, 22.9, 20.9, 17.4, 11.0.
                
    
                
                
    References:
    
                
    
                    Liang, Yu-Yan;Huang, Huan;Li, Yang;Du, Rong-Kai;Li, Jing;Liu, Yong-Hong;Li, Shan;Zhang, Lei [Steroids,2020,vol. 157,art. no. 108594]
                
    
                
            
    
            
        
    
        
        
        
        
        
        
        
        
        
    
    

    
    
    
        
        
    Chenodeoxycholic acid Related Search: