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5265-18-9

CATHINONE synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: E.coli cells expressed epoxide hydrolase from Sphingomonas sp. HXN200 / aq. phosphate buffer; n-heptane / 30 h / 30 °C / Enzymatic reaction
2: NAD; recombinant alcohol dehydrogenase from Aromatoleum aromaticum; recombinant amine dehydrogenase variant from Rhodoccoccus sp.; ammonium formate / water / 50 °C / pH 8.5 / Enzymatic reaction

References:

Corrado, Maria L.;Knaus, Tanja;Mutti, Francesco G. [Green Chemistry,2019,vol. 21,# 23,p. 6246 - 6251]

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