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ChemicalBook CAS DataBase List carfentrazone-ethyl
128621-72-7

carfentrazone-ethyl synthesis

2synthesis methods
128639-02-1 Synthesis
CARFENTRAZONE-ETHYL

128639-02-1
98 suppliers
$60.00/10 mg

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Yield:128621-72-7 7.68 g

Reaction Conditions:

with water;sodium hydroxide in tetrahydrofuran at 20; for 5 h;

Steps:

1.1 (1) Preparation of Intermediate Carboxylic Acid (IV-1)
To a 250 ml reaction flask was added Carfentrazone-Ethyl (10.30 g, 25 mmol) and 80 ml of tetrahydrofuran.Stir until completely dissolved and add sodium hydroxide (1.00 g,A solution of 25 mmol) and water (100 ml) is naturally raised to room temperature and stirred for 5 hours.Stop the reaction, add 100 ml ethyl acetate extraction, the aqueous phase acidified with concentrated hydrochloric acid, filtered,The filter cake was dried to give 7.68 g of intermediate acid IV-1.

References:

Shenyang Sinochem Pesticide Chemical Research And Development Co., Ltd.;Cheng Xueming;Liang Shuang;Ma Hongjuan;Hou Yuehua;Cui Dongliang;Liu Pengfei;Li Bin CN106831618, 2017, A Location in patent:Paragraph 0080; 0081; 0082

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