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ChemicalBook CAS DataBase List C-(1H-INDOL-7-YL)-METHYLAMINE
408356-52-5

C-(1H-INDOL-7-YL)-METHYLAMINE synthesis

2synthesis methods
-

Yield:408356-52-5 100%

Reaction Conditions:

with hydrogen;palladium dihydroxide in methanol; for 4 h;

Steps:

1.1.44

(Z)-lH-indole-7-carbaldehyde oxime (lOOmg, 0.60 mmol) in MeOH (5 mL), Pd(OH)2 (50 mg) was added and stirred under hydrogen atmosphere (balloon pressure) for 4h. Reaction mixture was then filtered and solvent evaporated to yield (lH-indol-7- yl)methanamine in quantitative yield.

References:

WO2009/42694,2009,A1 Location in patent:Page/Page column 90-91

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