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ChemicalBook CAS DataBase List C 1311
138154-39-9

C 1311 synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1.1: N,N-dimethyl-aniline / Inert atmosphere
2.1: trichlorophosphate / 1,2-dichloro-ethane / 90 °C
3.1: N,N-dimethyl-formamide / 4 h / Reflux
4.1: hydrazine hydrate / tetrahydrofuran / 24 h / 20 °C
4.2: 0.5 h / pH 3
5.1: 24 h / Reflux

References:

Dunstan, Mark S.;Barnes, John;Humphries, Matthew;Whitehead, Roger C.;Bryce, Richard A.;Leys, David;Stratford, Ian J.;Nolan, Karen A. [Journal of Medicinal Chemistry,2011,vol. 54,# 19,p. 6597 - 6611]

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