Bromoacetyl chloride synthesis
- Product Name:Bromoacetyl chloride
- CAS Number:22118-09-8
- Molecular formula:C2H2BrClO
- Molecular Weight:157.39
79-08-3
312 suppliers
$9.00/1g
22118-09-8
174 suppliers
$21.21/10gm:
Yield:22118-09-8 95.23%
Reaction Conditions:
with thionyl chloride for 2 h;Reflux;Inert atmosphere;
Steps:
Synthesis of bromoacetyl chloride (1)
A stirred solution of bromoacetic acid (13.9 g, 100 mmol) in thionyl chloride (10 mL) was refluxed for 2 h. The reaction mixture was concentrated in vacuo to remove excess thionyl chloride. The residue was evaporated under reduced pressure, and the distillation cut between 48 and 49C/1.6 kPa was collected as a slightly yellow transparent liquid with yield of 15 g (95 mmol, 95.23 %)
References:
Wan, Fuxian;Liu, Mingjie;Zhang, Junzheng;Li, Ying;Jiang, Lin [Research on Chemical Intermediates,2015,vol. 41,# 8,p. 5109 - 5119]
98-88-4
585 suppliers
$10.00/5g
79-08-3
312 suppliers
$9.00/1g
22118-09-8
174 suppliers
$21.21/10gm:
