ChemicalBook CAS DataBase List Benzyltrimethylammonium chloride

Benzyltrimethylammonium chloride synthesis

4synthesis methods

Product Name:Benzyltrimethylammonium chloride
CAS Number:56-93-9
Molecular formula:C10H16ClN
Molecular Weight:185.69

100-44-7 Synthesis

100-44-7
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$13.50/250G

75-50-3
262 suppliers
$15.00/25ml

56-93-9
476 suppliers
$5.00/25g

Yield:56-93-9 98%

Reaction Conditions:

in tetrahydrofuran;ethanol at 20; for 24 h;

Steps:

Preparation of N,N,N-trimethyl-1-phenylmethanaminium chloride and bromide(1i-1j)

General procedure: To a 100 mL of round-bottom flask were added a solution of benzyl bromide orchloride (10 mmol, 1 equiv.) in THF (20 mL), and a solution of 33 w% trimethylaminein EtOH (2.9 g, 15 mmol, 1.5 equiv.,) with stirring. The resulting mixture wasstirred at room temperature for 24 h. After the solvent was removed in vacuo, Et2O(40 mL) was added into the mixture. The precipitate was filtered and washed byEt2O(3 × 10 mL), and then, the resulting solid was dried under vacuum to give thewhite solid

References:

Zhong, Chuntao;Tang, Huiling;Cui, Benqiang;Shi, Yanhui;Cao, Changsheng [Research on Chemical Intermediates,2022,vol. 48,# 10,p. 4017 - 4032]