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133188-66-6

Benzenepropanoyl chloride, 4-fluoro- synthesis

4synthesis methods
-

Yield:3096-81-9 75.3 g (100%)

Reaction Conditions:

with dichloro sulfoxide

Steps:

13.c c)

c) Preparation of 7-Fluoro-1-tetralone A mixture of 4-(4-fluorophenyl)butyric acid (68.2 g, 0.37 mol) and thionyl chloride (155 g, 1.3 mol) was refluxed for 1.25 h. The mixture was concentrated in vacuo to give 75.3 g (100%) of 4-(4-fluorophenyl)butyryl chloride)

References:

US5872118,1999,A