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ChemicalBook CAS DataBase List Anlotinib
1058156-90-3

Anlotinib synthesis

2synthesis methods
7-Quinolinol, 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-

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Anlotinib

1058156-90-3
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 75 - 85 °C
2: hydrogenchloride / ethanol / 20 °C / Cooling with ice

References:

Shanghai Bopunuo Science And Technology Co., Ltd.;Guo Peng;Zhu Wenfeng CN108864050, 2018, A

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