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ChemicalBook CAS DataBase List ethyl 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydroquinoline-4-oxo-3-carboxyla
99696-21-6

ethyl 8-chloro-1-cyclopropyl-6,7-difluoro-1,4-dihydroquinoline-4-oxo-3-carboxyla synthesis

1synthesis methods
Benzenepropanoic acid, 3-chloro-α-[(cyclopropylamino)methylene]-2,4,5-trifluoro-β-oxo-, ethyl ester

101987-88-6
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Yield:-

Reaction Conditions:

with sodium hydride in 1,4-dioxane; for 2 h;Ambient temperature;

References:

Kimura;Atarashi;Kawakami;Sato;Hayakawa [Journal of Medicinal Chemistry,1994,vol. 37,# 20,p. 3344 - 3352]

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